This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take this guidance fully into account, and specifically any special arrangements relating to the introduction of new inter...

Texto completo

Before initiation of antibiotic treatment, a specimen should be obtained for microbiological diagnostics. The first choice is an ulcer biopsy, as this method has the best microbiological diagnostic precision. It is important that the clinician arrives at the choice of diagnostics in consultation with the...

Texto completo